The other tiers are easily outclassing the F-Tier. We’ll be sincere and admit that these are the worst civilizations to play.
Knowing all the available leaders in the game will grant you a lot of help, and that’s why you should take a look at the following tier lists: The ultimate goal in Civilization 6 is to become the most successful civ, as defined by different victory conditions, after leading your people from the Stone Age to the Information Age. In that case, there is one sure way of doing all that virtually. Suppose you like the idea of expanding an empire, advancing a culture, building an entire civilization and fighting against the greatest leaders in history.
ProClockers has put together a Civ 6 Tier List which summarizes some of the best Civs and Leaders in the game. Civilization 6 has 45 leaders from which you can choose, so it may feel intimidating when you’re trying to decide what leader to pick.